Alternative splicing produces nanog protein variants with different capacities for self-renewal and pluripotency in embryonic stem cells

Keyphrases

• Self-renewal 100%
• Embryonic Stem Cells 100%
• Alternative Splicing 100%
• Pluripotency 100%
• Nanog 100%
• Protein Variants 100%
• Nanog Protein 100%
• Protein-coding Genes 37%
• Serine 2 25%
• Coding Capacity 25%
• Biological Processes 12%
• Octamer-binding Transcription Factor 4 (OCT4) 12%
• Biological Function 12%
• Tryptophan 12%
• Exon 12%
• Gene Structure 12%
• Point mutation 12%
• Germ Layers 12%
• Sex-determining Region Y-box 2 (SOX2) 12%
• N-terminal Domain 12%
• Mutation Analysis 12%
• Homeodomain Transcription Factor 12%
• Novel Variants 12%
• Stem Cell Self-renewal 12%
• Conditional Knockout 12%
• WR Domain 12%
• Pluripotency Genes 12%
• Gene Signature 12%

Biochemistry, Genetics and Molecular Biology

• Nanog 100%
• Embryonic Stem Cell 100%
• Alternative Splicing 100%
• Serine 18%
• Exon 9%
• Gene Structure 9%
• N-Terminus 9%
• Homeodomain 9%
• Gene Signature 9%
• Biological Functions 9%
• Point Mutation 9%
• C-Terminus 9%
• Biological Phenomena and Functions Concerning the Entire Organism 9%
• Stem Cell Self-Renewal 9%
• Germ Layer 9%
• Transcription Factors 9%
• Tryptophan 9%