Altered dendritic orientation of hypothalamic neurons from genetically obese (ob/ob) mice

D. A. Bereiter, B. Jeanrenaud

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Abstract

Individual Golgi-stained neurons from the ventromedial nucleus (VMN) and lateral hypothalamic area (LHA) were analyzed from genetically obese and lean mice. No strain differences were noted for the number of dendrites or the position of dendritic branch points as a function of distance from the cell body for any of the hypothalamic areas sampled. However, both LHA and VMN neurons showed altered dendritic orientation between mouse strains.

Original languageEnglish (US)
Pages (from-to)201-206
Number of pages6
JournalBrain Research
Volume202
Issue number1
DOIs
StatePublished - Nov 24 1980

Bibliographical note

Funding Information:
The authors wish to thank Mrs. Yva Gros for technical assistance and Mrs. C. McVeigh for the preparation of the manuscript. This work was funded by Grants 3.1540.77 and 3.637.80 of the Swiss National Science Foundation, Berne (Switzerland), by Grant 1 R01 AM 25220-01 of the National Institutes of Health, Bethesda, Md. (U.S.A.) and by a Grant-in-Aid of Nestl6 S.A., Vevey (Switzerland).

Keywords

  • dendritic organization
  • genetically obese mouse
  • hypothalamus

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