Altered cell walls of Staphylococcus aureus resistant to methicillin.

L. D. Sabath; C. D. Leaf; D. A. Gerstein; M. Finland

doi:10.1038/2251074a0

Altered cell walls of Staphylococcus aureus resistant to methicillin.

L. D. Sabath, C. D. Leaf, D. A. Gerstein, M. Finland

Medicine - Infectious Disease and International Medicine

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

Abstract

METHICILLIN-resistant (MR) strains of Staphylococcus aureus, those capable of multiplying in the presence of 12.5 g of methicillin/ml. (eight or more times that tolerated by methicillin-sensitive (MS) strains), are also resistant to other commonly used antibiotics, including other semi-synthetic penicillins and cephalosporins^1-7. They can cause major disease^6-11 and thus may pose a serious therapeutic problem.

Original language	English (US)
Pages (from-to)	1074
Number of pages	1
Journal	Nature
Volume	225
Issue number	237
DOIs	https://doi.org/10.1038/2251074a0
State	Published - Mar 14 1970

Keywords

Cell Wall/de [Drug Effects]
Lysostaphin/pd [Pharmacology]
Methicillin/pd [Pharmacology]
Penicillin Resistance
Staphylococcus/de [Drug Effects]

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title = "Altered cell walls of Staphylococcus aureus resistant to methicillin.",

abstract = "METHICILLIN-resistant (MR) strains of Staphylococcus aureus, those capable of multiplying in the presence of 12.5 g of methicillin/ml. (eight or more times that tolerated by methicillin-sensitive (MS) strains), are also resistant to other commonly used antibiotics, including other semi-synthetic penicillins and cephalosporins1-7. They can cause major disease6-11 and thus may pose a serious therapeutic problem.",

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author = "Sabath, {L. D.} and Leaf, {C. D.} and Gerstein, {D. A.} and M. Finland",

year = "1970",

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T1 - Altered cell walls of Staphylococcus aureus resistant to methicillin.

AU - Sabath, L. D.

AU - Leaf, C. D.

AU - Gerstein, D. A.

AU - Finland, M.

PY - 1970/3/14

Y1 - 1970/3/14

N2 - METHICILLIN-resistant (MR) strains of Staphylococcus aureus, those capable of multiplying in the presence of 12.5 g of methicillin/ml. (eight or more times that tolerated by methicillin-sensitive (MS) strains), are also resistant to other commonly used antibiotics, including other semi-synthetic penicillins and cephalosporins1-7. They can cause major disease6-11 and thus may pose a serious therapeutic problem.

AB - METHICILLIN-resistant (MR) strains of Staphylococcus aureus, those capable of multiplying in the presence of 12.5 g of methicillin/ml. (eight or more times that tolerated by methicillin-sensitive (MS) strains), are also resistant to other commonly used antibiotics, including other semi-synthetic penicillins and cephalosporins1-7. They can cause major disease6-11 and thus may pose a serious therapeutic problem.

KW - Cell Wall/de [Drug Effects]

KW - Lysostaphin/pd [Pharmacology]

KW - Methicillin/pd [Pharmacology]

KW - Penicillin Resistance

KW - Staphylococcus/de [Drug Effects]

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DO - 10.1038/2251074a0

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SP - 1074

JO - Nature

JF - Nature

IS - 237

ER -

Altered cell walls of Staphylococcus aureus resistant to methicillin.

Abstract

Keywords

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