Alterations of evoked potentials in the medial lemniscus of the rat due to acute and chronic elevations in blood pressure

James T. Garsik, Walter C. Low, David Whitehorn

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

The influence of elevated blood pressure on evoked field potentials in the medial lemniscus induced by peripheral stimulation was studied in the rat. Acute hypertension as a result of phenylephrine infusions reduced the size of this response in individual Wistar Kyot rats. Chronic renal hypertension in Sprague-Dawley rats also cuased a reduction in the dorsal column-medial lemniscal evoked response. These results confirm an inhibitory action of elevated blood pressure on transmission in through the dorsal column nuclei.

Original languageEnglish (US)
Pages (from-to)380-383
Number of pages4
JournalBrain Research
Volume306
Issue number1-2
DOIs
StatePublished - Jul 23 1984

Keywords

  • experimental hypertension
  • medial lemniscus
  • sensory modulation

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