Keyphrases
Flexible Loop
100%
Enthalpy-driven
100%
Fosfomycin
100%
1-deoxy-D-xylulose 5-phosphate Reductoisomerase
100%
Water Network
40%
Mycobacterium Tuberculosis (M. tb)
20%
Drug Target
20%
Isoprenoid Synthesis
20%
Hydrogen Bonding Interaction
20%
Ligand Binding
20%
Conserved Residues
20%
Steady-state Kinetics
20%
Kcat
20%
Rate Limiting
20%
Isothermal Titration Calorimetry
20%
X-ray Crystal Structure
20%
Product Release
20%
Deuterium Isotope Effect
20%
Enthalpy Difference
20%
Total Binding Energy
20%
Infectious Microorganisms
20%
Phosphonate Groups
20%
Enzyme Chemistry
20%
Structured Water
20%
Methylerythritol Phosphate Pathway
20%
Biochemistry, Genetics and Molecular Biology
Enthalpy
100%
Flexible Loop
100%
Xylulose 5-Phosphate
100%
Fosmidomycin
100%
Xylulose
100%
Wild Type
60%
X Ray
20%
Crystal Structure
20%
Hydrogen Bond
20%
Ligand Binding
20%
Kinetic Isotope Effect
20%
Isoprenoids Biosynthesis
20%
Microorganism
20%
Steady State
20%
Turnover Number
20%
Binding Energy
20%
Isothermal Titration Calorimetry
20%
Enzyme Chemistry
20%
Mycobacterium Tuberculosis
20%
Erythritol
20%