Allergy to methyldibromoglutaronitrile/phenoxyethanol (Euxyl K 400): Regulatory issues, epidemiology, clinical characteristics, and management

Angela E. Aakhus; Erin M. Warshaw

doi:10.2310/6620.2011.10081

Allergy to methyldibromoglutaronitrile/phenoxyethanol (Euxyl K 400): Regulatory issues, epidemiology, clinical characteristics, and management

Angela E. Aakhus, Erin M. Warshaw

Dermatology

Research output: Contribution to journal › Review article › peer-review

25 Scopus citations

Abstract

Methyldibromoglutaronitrile/phenoxyethanol (Euxyl K 400) is a preservative found in both personal care products and industrial sources. Although Euxyl K 400 initially appeared to have low sensitizing potential, increased prevalence of contact allergy to Euxyl K 400 led to regulatory intervention. This review summarizes the history, epidemiology, and management of contact allergy to Euxyl K 400. Issues related to patch-test preparations are also discussed.

Original language	English (US)
Pages (from-to)	127-140
Number of pages	14
Journal	Dermatitis
Volume	22
Issue number	3
DOIs	https://doi.org/10.2310/6620.2011.10081
State	Published - Jun 2011

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abstract = "Methyldibromoglutaronitrile/phenoxyethanol (Euxyl K 400) is a preservative found in both personal care products and industrial sources. Although Euxyl K 400 initially appeared to have low sensitizing potential, increased prevalence of contact allergy to Euxyl K 400 led to regulatory intervention. This review summarizes the history, epidemiology, and management of contact allergy to Euxyl K 400. Issues related to patch-test preparations are also discussed.",

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AB - Methyldibromoglutaronitrile/phenoxyethanol (Euxyl K 400) is a preservative found in both personal care products and industrial sources. Although Euxyl K 400 initially appeared to have low sensitizing potential, increased prevalence of contact allergy to Euxyl K 400 led to regulatory intervention. This review summarizes the history, epidemiology, and management of contact allergy to Euxyl K 400. Issues related to patch-test preparations are also discussed.

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Allergy to methyldibromoglutaronitrile/phenoxyethanol (Euxyl K 400): Regulatory issues, epidemiology, clinical characteristics, and management

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