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Alkylating agents in bronchogenic carcinoma

  • Robert A. Green
  • , Edward Humphrey
  • , Henry Close
  • , Mary Ellen Patno

Research output: Contribution to journalArticlepeer-review

Abstract

A large number of patients in a group of Veterans Administration Hospitals received a variety of alkylating agents in studies in which these agents were randomized with an inert compound. Intravenous cyclophosphamide, and possibly nitrogen mustard, had a slight favorable influence upon survival for all patients. A difference between the two agents was seen: patients with squamous cell carcinoma appeared to respond best to nitrogen mustard therapy and patients with small cell undifferentiated carcinoma to cyclophosphamide therapy, in fairly striking fashion. Over-all influences upon survival, however, were not remarkable.

Original languageEnglish (US)
Pages (from-to)516-525
Number of pages10
JournalThe American Journal of Medicine
Volume46
Issue number4
DOIs
StatePublished - Apr 1969
Externally publishedYes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

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