Alkaloids derived from tryptophan: Terpenoid indole alkaloids

Shilpa Ramani; Nandadevi Patil; Suhas Nimbalkar; Chelliah Jayabaskaran

doi:10.1007/978-3-642-22144-6_21

Alkaloids derived from tryptophan: Terpenoid indole alkaloids

Shilpa Ramani, Nandadevi Patil, Suhas Nimbalkar, Chelliah Jayabaskaran

Neurosurgery

Research output: Chapter in Book/Report/Conference proceeding › Chapter

14 Scopus citations

Abstract

L-Tryptophan is an indole ring containing aromatic amino acid derived via the shikimate pathway. The tryptophan-derived alkaloids are found in eight families, of which, Apocynaceae, Loganiaceae, Rubiaceae, and Nyssaceae are the best sources. The alkaloids under discussion are the Catharanthus alkaloids, namely, ajmalicine, tabersonine, catharanthine, vindoline, vinblastine, vincristine and vincamine as well as terpenoid alkaloids derived from other families, namely, yohimbine, reserpine, strychnine, brucine, and ellipticine. The above-mentioned alkaloids are pharmacologically very important and hence extremely valuable. This chapter describes various aspects of the tryptophan-derived alkaloids like occurrence, biological activity, phytochemistry, and commercial and biotechnological aspects.

Original language	English (US)
Title of host publication	Natural Products
Subtitle of host publication	Phytochemistry, Botany and Metabolism of Alkaloids, Phenolics and Terpenes
Publisher	Springer Berlin Heidelberg
Pages	575-604
Number of pages	30
ISBN (Electronic)	9783642221446
ISBN (Print)	9783642221439
DOIs	https://doi.org/10.1007/978-3-642-22144-6_21
State	Published - Jan 1 2013

Bibliographical note

Publisher Copyright:
© Springer-Verlag Berlin Heidelberg 2013.

Keywords

Catharanthus
TIA
Tryptophan-derived alkaloids

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10.1007/978-3-642-22144-6_21

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AU - Patil, Nandadevi

AU - Nimbalkar, Suhas

AU - Jayabaskaran, Chelliah

PY - 2013/1/1

Y1 - 2013/1/1

N2 - L-Tryptophan is an indole ring containing aromatic amino acid derived via the shikimate pathway. The tryptophan-derived alkaloids are found in eight families, of which, Apocynaceae, Loganiaceae, Rubiaceae, and Nyssaceae are the best sources. The alkaloids under discussion are the Catharanthus alkaloids, namely, ajmalicine, tabersonine, catharanthine, vindoline, vinblastine, vincristine and vincamine as well as terpenoid alkaloids derived from other families, namely, yohimbine, reserpine, strychnine, brucine, and ellipticine. The above-mentioned alkaloids are pharmacologically very important and hence extremely valuable. This chapter describes various aspects of the tryptophan-derived alkaloids like occurrence, biological activity, phytochemistry, and commercial and biotechnological aspects.

AB - L-Tryptophan is an indole ring containing aromatic amino acid derived via the shikimate pathway. The tryptophan-derived alkaloids are found in eight families, of which, Apocynaceae, Loganiaceae, Rubiaceae, and Nyssaceae are the best sources. The alkaloids under discussion are the Catharanthus alkaloids, namely, ajmalicine, tabersonine, catharanthine, vindoline, vinblastine, vincristine and vincamine as well as terpenoid alkaloids derived from other families, namely, yohimbine, reserpine, strychnine, brucine, and ellipticine. The above-mentioned alkaloids are pharmacologically very important and hence extremely valuable. This chapter describes various aspects of the tryptophan-derived alkaloids like occurrence, biological activity, phytochemistry, and commercial and biotechnological aspects.

KW - Catharanthus

KW - TIA

KW - Tryptophan-derived alkaloids

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ER -

Alkaloids derived from tryptophan: Terpenoid indole alkaloids

Abstract

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