Algorithm for the diagnosis and management of suspected pump thrombus

Daniel J. Goldstein, Ranjit John, Christopher Salerno, Scott Silvestry, Nader Moazami, Douglas Horstmanshof, Robert Adamson, Andrew Boyle, Mark Zucker, Joseph Rogers, Stuart Russell, James Long, Francis Pagani, Ulrich Jorde

Research output: Contribution to journalEditorialpeer-review

197 Scopus citations


Pump thrombosis is a dreaded complication of long-term implantable ventricular assist devices. No guidance exists regarding the diagnosis and management of this entity despite its significant morbidity. After considerable thought and deliberation, a group of leading investigators in the field of mechanical support propose an algorithm for the diagnosis and management of this vexing entity based on clinical symptoms and serologic and imaging studies.

Original languageEnglish (US)
Pages (from-to)667-670
Number of pages4
JournalJournal of Heart and Lung Transplantation
Issue number7
StatePublished - Jul 2013

Bibliographical note

Funding Information:
The investigators acknowledge the support of Thoratec Corporation for sponsoring the bleeding and thrombosis workgroup and facilitating the meetings and conference calls.

Funding Information:
Daniel Goldstein is a consultant and honoraria at Thoratec Inc. and a consultant at HeartWare Inc. Nader Moazami is a consultant at Thoratec Inc. Andrew Boyle is a consultant and honoraria at Thoratec Inc. Ulrich Jorde is a consultant at Thoratec Inc., HeartWare Inc., and Jarvik Inc. Scott Silvestry is associated with Research Support/Grants at Thoratec Inc, Abiomed Inc- educational grant and is a consultant at Thoratec Inc., and HeartWare Inc. Franc Pagani is a contract researcher at HeartWare Inc. Joseph Rogers is a Thoratec Inc. consultant and HeartWare Inc. principal investigator. Chris Salerno is a Thoratec Inc. consultant. Ranjit John received a research grant from Thoratec and HeartWare. Robert Adamson is associated with Thoratec’s Speaker Bureau as well as a being a surgical trainer for the Heart Mate LVAD. Douglas Horstmanshof received a speaking, consultant, and research grant from Thoratec Inc. James Long provides educational and advisory services for Thoratec Inc.

Copyright 2019 Elsevier B.V., All rights reserved.


  • continuous-flow pump
  • hemolysis
  • power spikes
  • thrombus
  • ventricular assist device


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