Alcohol interaction with cocaine, methamphetamine, opioids, nicotine, cannabis, and γ-hydroxybutyric acid

Research output: Contribution to journalReview article

Abstract

Millions of people around the world drink alcoholic beverages to cope with the stress of modern lifestyle. Although moderate alcohol drinking may have some relaxing and euphoric effects, uncontrolled drinking exacerbates the problems associated with alcohol abuse that are exploding in quantity and intensity in the United States and around the world. Recently, mixing of alcohol with other drugs of abuse (such as opioids, cocaine, methamphetamine, nicotine, cannabis, and γ-hydroxybutyric acid) and medications has become an emerging trend, exacerbating the public health concerns. Mixing of alcohol with other drugs may additively or synergistically augment the seriousness of the adverse effects such as the withdrawal symptoms, cardiovascular disorders, liver damage, reproductive abnormalities, and behavioral abnormalities. Despite the seriousness of the situation, possible mechanisms underlying the interactions is not yet understood. This has been one of the key hindrances in developing effective treatments. Therefore, the aim of this article is to review the consequences of alcohol's interaction with other drugs and decipher the underlying mechanisms.

Original languageEnglish (US)
Article number16
JournalBiomedicines
Volume7
Issue number1
DOIs
StatePublished - Mar 1 2019

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Hydroxybutyrates
Methamphetamine
Cannabis
Nicotine
Cocaine
Opioid Analgesics
Alcohols
Alcoholic Beverages
Substance Withdrawal Syndrome
Street Drugs
Alcohol Drinking
Pharmaceutical Preparations
Alcoholism
Drinking
Life Style
Public Health
Public health
Liver

Keywords

  • Addiction
  • Cocaine
  • Marijuana
  • Methamphetamine (METH)
  • Nicotine
  • Opioids
  • Withdrawal
  • alcohol
  • γ-aminobutyric acid (GABA)

PubMed: MeSH publication types

  • Journal Article
  • Review

Cite this

Alcohol interaction with cocaine, methamphetamine, opioids, nicotine, cannabis, and γ-hydroxybutyric acid. / Singh, Ashok K.

In: Biomedicines, Vol. 7, No. 1, 16, 01.03.2019.

Research output: Contribution to journalReview article

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