Aging does not alter muscarinic receptor-mediated inhibition of cyclic AMP formation in the striatum and hippocampus

Elsayed A M Abdallah; Wanida S. Pou; Esam E. El-Fakahany

doi:10.1016/0006-8993(90)90133-V

Aging does not alter muscarinic receptor-mediated inhibition of cyclic AMP formation in the striatum and hippocampus

Elsayed A M Abdallah, Wanida S. Pou, Esam E. El-Fakahany

Pharmacy Research and Graduate Education

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Abstract

The effects of aging on the inhibition of forskolin-stimulated cyclic AMP formation by muscarinic receptors were investigated. There were no detectable changes in the magnitude of maximal inhibition by carbamylcholine or the potency of the agonist in inducing this response in either the striatum or hippocampus obtained from young or old Fisher 344 rats.

Original language	English (US)
Pages (from-to)	234-236
Number of pages	3
Journal	Brain Research
Volume	534
Issue number	1-2
DOIs	https://doi.org/10.1016/0006-8993(90)90133-V
State	Published - Nov 26 1990

Keywords

Aging
Cyclic adenosine monophosphate
Fischer 344 rat
Hippocampus
Muscarinic
Striatum

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10.1016/0006-8993(90)90133-V

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abstract = "The effects of aging on the inhibition of forskolin-stimulated cyclic AMP formation by muscarinic receptors were investigated. There were no detectable changes in the magnitude of maximal inhibition by carbamylcholine or the potency of the agonist in inducing this response in either the striatum or hippocampus obtained from young or old Fisher 344 rats.",

keywords = "Aging, Cyclic adenosine monophosphate, Fischer 344 rat, Hippocampus, Muscarinic, Striatum",

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AU - Abdallah, Elsayed A M

AU - Pou, Wanida S.

AU - El-Fakahany, Esam E.

PY - 1990/11/26

Y1 - 1990/11/26

N2 - The effects of aging on the inhibition of forskolin-stimulated cyclic AMP formation by muscarinic receptors were investigated. There were no detectable changes in the magnitude of maximal inhibition by carbamylcholine or the potency of the agonist in inducing this response in either the striatum or hippocampus obtained from young or old Fisher 344 rats.

AB - The effects of aging on the inhibition of forskolin-stimulated cyclic AMP formation by muscarinic receptors were investigated. There were no detectable changes in the magnitude of maximal inhibition by carbamylcholine or the potency of the agonist in inducing this response in either the striatum or hippocampus obtained from young or old Fisher 344 rats.

KW - Aging

KW - Cyclic adenosine monophosphate

KW - Fischer 344 rat

KW - Hippocampus

KW - Muscarinic

KW - Striatum

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JO - Brain Research

JF - Brain Research

IS - 1-2

ER -

Aging does not alter muscarinic receptor-mediated inhibition of cyclic AMP formation in the striatum and hippocampus

Abstract

Keywords

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