Abstract
Aging is associated with a progressive decline of muscle mass, strength, and quality, a condition described as sarcopenia of aging. Despite the significance of skeletal muscle atrophy, the mechanisms responsible for the deterioration of muscle performance are only partially understood. The purpose of this review is to highlight cellular, molecular, and biochemical changes that contribute to age-related muscle dysfunction.
Original language | English (US) |
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Pages (from-to) | 106-111 |
Number of pages | 6 |
Journal | Experimental Gerontology |
Volume | 44 |
Issue number | 1-2 |
DOIs | |
State | Published - Jan 2009 |
Keywords
- Actin
- Aged muscle
- Enzymatic activity
- Myosin
- Oxidative modifications