AFM study of interactions between peptide-amphiphile biomimetic surfaces and integrins

Efrosini Kokkoli, Matthew Tirrell

Research output: Contribution to journalConference articlepeer-review

Abstract

Bioartificial membranes that mimic the extracellular matrix protein, fibronectin, are constructed from mixtures of peptide-amphiphiles and polyethylene glycol amphiphilic molecules and are deposited on a surface by the Langmuir-Blodgett technique. The effect of different parameters such as different ions, the loading rate and different peptide conformations are determined on the dynamics of the α5 β1-GRGDSP interaction using the AFM.

Original languageEnglish (US)
Pages (from-to)S-14
JournalAnnals of Biomedical Engineering
Volume28
Issue numberSUPPL. 1
StatePublished - 2000
Event2000 Annual Fall Meeting of the Biomedical Engineering Society - Washington, WA, USA
Duration: Oct 12 2000Oct 14 2000

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