Advances in thrombolytics and mechanical devices for treatment of acute ischemic stroke

Ammar Alkawi; Jawad F. Kirmani; Nazli Janjua; Ismail Khatri; Shafiuddin Ahmed; Afshin A. Divani; Adrian I. Qureshi

doi:10.1179/016164105X25306

Advances in thrombolytics and mechanical devices for treatment of acute ischemic stroke

Ammar Alkawi, Jawad F. Kirmani, Nazli Janjua, Ismail Khatri, Shafiuddin Ahmed, Afshin A. Divani, Adrian I. Qureshi

Neurology

Research output: Contribution to journal › Review article › peer-review

4 Scopus citations

Abstract

Stroke is a leading cause of death and disability. Recently, there have been advances in the treatment of acute ischemic stroke aimed at re-establishing blood flow to the affected area in an effort to save the ischemic penumbra surrounding the area of infarction. This is achieved by the use of thrombolytics intravenously or intra-arterially. The use of mechanical devices facilitates the function of pharmacological agents used in addition to minimizing the associated risks. In this review, we first discuss the therapeutic potentials and strategies employed in using different thrombolytics in management of acute ischemic stroke. Subsequently, we discuss the recent advances and therapeutic applications of mechanical devices in this field.

Original language	English (US)
Journal	Neurological Research
Volume	27
Issue number	SUPPL. 1
DOIs	https://doi.org/10.1179/016164105X25306
State	Published - Oct 1 2005

Keywords

Mechanical devices
Recanalization
Stents
Stroke
Thrombolytics

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1179/016164105X25306

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abstract = "Stroke is a leading cause of death and disability. Recently, there have been advances in the treatment of acute ischemic stroke aimed at re-establishing blood flow to the affected area in an effort to save the ischemic penumbra surrounding the area of infarction. This is achieved by the use of thrombolytics intravenously or intra-arterially. The use of mechanical devices facilitates the function of pharmacological agents used in addition to minimizing the associated risks. In this review, we first discuss the therapeutic potentials and strategies employed in using different thrombolytics in management of acute ischemic stroke. Subsequently, we discuss the recent advances and therapeutic applications of mechanical devices in this field.",

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AU - Alkawi, Ammar

AU - Kirmani, Jawad F.

AU - Janjua, Nazli

AU - Khatri, Ismail

AU - Ahmed, Shafiuddin

AU - Divani, Afshin A.

AU - Qureshi, Adrian I.

PY - 2005/10/1

Y1 - 2005/10/1

N2 - Stroke is a leading cause of death and disability. Recently, there have been advances in the treatment of acute ischemic stroke aimed at re-establishing blood flow to the affected area in an effort to save the ischemic penumbra surrounding the area of infarction. This is achieved by the use of thrombolytics intravenously or intra-arterially. The use of mechanical devices facilitates the function of pharmacological agents used in addition to minimizing the associated risks. In this review, we first discuss the therapeutic potentials and strategies employed in using different thrombolytics in management of acute ischemic stroke. Subsequently, we discuss the recent advances and therapeutic applications of mechanical devices in this field.

AB - Stroke is a leading cause of death and disability. Recently, there have been advances in the treatment of acute ischemic stroke aimed at re-establishing blood flow to the affected area in an effort to save the ischemic penumbra surrounding the area of infarction. This is achieved by the use of thrombolytics intravenously or intra-arterially. The use of mechanical devices facilitates the function of pharmacological agents used in addition to minimizing the associated risks. In this review, we first discuss the therapeutic potentials and strategies employed in using different thrombolytics in management of acute ischemic stroke. Subsequently, we discuss the recent advances and therapeutic applications of mechanical devices in this field.

KW - Mechanical devices

KW - Recanalization

KW - Stents

KW - Stroke

KW - Thrombolytics

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Advances in thrombolytics and mechanical devices for treatment of acute ischemic stroke

Abstract

Keywords

UN SDGs

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