The 2nd Scripps Florida Symposium on The Biology of Aging entitled ‘Advances in Therapeutic Approaches to Extend Healthspan’ was held on January 22nd–25th, 2017 at The Scripps Research Institute in Jupiter, Florida. The meeting highlighted a variety of therapeutic approaches in animal models of aging that either are or soon will be in clinic trials. For example, drugs targeting senescent cells, metformin, rapalogs, NAD precursors, young plasma, mitochondrial-targeted free radical scavengers, stem cells, and stem cell factors all have shown significant preclinical efficacy. This perspective, based on presentations and discussions at the symposium, outlines the current and future state of development of therapeutic approaches to extend human healthspan.
|Original language||English (US)|
|Number of pages||5|
|State||Published - Aug 2017|
Bibliographical noteFunding Information:
The authors also would like to thank the sponsors of the Scripps Florida Symposium including Elizabeth Fago, Nuvista Institute for Healthy Living, Joseph A. Pesenti & Bernice Fain Pesenti Foundation, Novartis, Florida Power and Light, Jupiter Medical Center, American Federation of Aging Research, Chip Block, and Leanna Landsman. P.R. and L.J.N are supported by Program Project Grant AG043376 from the National Institutes of Health. The authors would like to thank Drs. Matthew Yousefzadeh, Aditi Gurkar, and Robert Brooks for edits and comments on the manuscript. The funding sources were duplicated.
© 2017 The Authors. Aging Cell published by the Anatomical Society and John Wiley & Sons Ltd.