Advances and challenges in immunotherapy for solid organ and hematopoietic stem cell transplantation

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Abstract

Although major advances have been made in solid organ and hematopoietic stem cell transplantation in the last 50 years, big challenges remain. This review outlines the current immunological limitations for hematopoietic stem cell and solid organ transplantation and discusses new immune-modulating therapies in preclinical development and in clinical trials that may allow these obstacles to be overcome.

Original languageEnglish (US)
Article number280rv2
JournalScience Translational Medicine
Volume7
Issue number280
DOIs
StatePublished - Mar 25 2015

Bibliographical note

Publisher Copyright:
© 2015, AAAS. All rights reserved.

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