Spinal cord injury (SCI) is a complex and devastating condition characterized by disruption of descending, ascending, and intrinsic spinal circuitries resulting in chronic neurologic deficits. In addition to limb and trunk sensorimotor deficits, SCI also damages the autonomic neurocircuitry, including the motor networks which support respiration and cough. A high cervical SCI (for example at C2-3) can cause complete respiratory paralysis, and even lower cervical or thoracic lesions commonly result in partial respiratory impairment. Although electrical phrenic respiration can restore ventilator-independent breathing in selected candidates, only a small subset of affected individuals can benefit from this technology at this moment. The present chapter discusses the challenges and potentials of spinal cord stimulation and, more specific, of the intercostal stimulation for restoring respiratory function.
|Original language||English (US)|
|Title of host publication||The Handbook of Neuromodulation (2 Volume Set)|
|Subtitle of host publication||Volme 1|
|Publisher||Nova Science Publishers, Inc.|
|Number of pages||16|
|State||Published - Jan 1 2022|
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© 2022 by Nova Science Publishers, Inc.