TY - JOUR
T1 - Advanced HIV Disease among Males and Females Initiating HIV Care in Rural Ethiopia
AU - Lifson, Alan Raymond
AU - Workneh, Sale
AU - Hailemichael, Abera
AU - MacLehose, Richard Fleming
AU - Horvath, Keith Joseph
AU - Hilk, Rose
AU - Sites, Anne Redmond
AU - Shenie, Tibebe
N1 - Publisher Copyright:
© The Author(s) 2019.
PY - 2019/5/17
Y1 - 2019/5/17
N2 - Despite recommendations for rapidly initiating HIV treatment, many persons in sub-Saharan Africa present to care with advanced HIV disease. Baseline survey and clinical data were collected on 1799 adults newly enrolling at 32 district hospitals and local health HIV clinics in rural Ethiopia. Among those with complete HIV disease information, advanced HIV disease (defined as CD4 count <200 cells/mm3 or World Health Organization [WHO] HIV clinical stage III or IV disease) was present in 66% of males and 56% of females (P <.001). Males (compared to females) had lower CD4 counts (287 cells/mm3 versus 345 cells/mm3), lower body mass index (19.3 kg/m2 versus 20.2 kg/m2), and more WHO stage III or IV disease (46% versus 37%), (P <.001). Men reported more chronic diarrhea, fevers, cough, pain, fatigue, and weight loss (P <.05). Most initiating care in this resource-limited setting had advanced HIV disease. Men had poorer health status, supporting the importance of earlier diagnosis, linkage to care, and initiation of antiretroviral therapy.
AB - Despite recommendations for rapidly initiating HIV treatment, many persons in sub-Saharan Africa present to care with advanced HIV disease. Baseline survey and clinical data were collected on 1799 adults newly enrolling at 32 district hospitals and local health HIV clinics in rural Ethiopia. Among those with complete HIV disease information, advanced HIV disease (defined as CD4 count <200 cells/mm3 or World Health Organization [WHO] HIV clinical stage III or IV disease) was present in 66% of males and 56% of females (P <.001). Males (compared to females) had lower CD4 counts (287 cells/mm3 versus 345 cells/mm3), lower body mass index (19.3 kg/m2 versus 20.2 kg/m2), and more WHO stage III or IV disease (46% versus 37%), (P <.001). Men reported more chronic diarrhea, fevers, cough, pain, fatigue, and weight loss (P <.05). Most initiating care in this resource-limited setting had advanced HIV disease. Men had poorer health status, supporting the importance of earlier diagnosis, linkage to care, and initiation of antiretroviral therapy.
KW - CD4 count
KW - HIV
KW - advanced HIV disease
KW - gender
KW - sub-Saharan Africa
UR - http://www.scopus.com/inward/record.url?scp=85066932876&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85066932876&partnerID=8YFLogxK
U2 - 10.1177/2325958219847199
DO - 10.1177/2325958219847199
M3 - Article
C2 - 31104543
AN - SCOPUS:85066932876
SN - 2325-9574
VL - 18
JO - Journal of the International Association of Providers of AIDS Care
JF - Journal of the International Association of Providers of AIDS Care
ER -