Adrenoleukodystrophy associated with vitiligo and ulcerative colitis

Raja A. Sawaya, Fadi H. Mourad, Samir Najjar, Muhammad Mikati, Gerald V. Raymond

Research output: Contribution to journalArticle

Abstract

Adrenoleukodystrophy (ALD) is an X-linked inherited disorder of lipid metabolism usually presenting in childhood or early adolescence. It is a progressive disease with symptoms of adrenal insufficiency and central nervous system demyelination. The pathology results from the accumulation of very long-chain fatty acids and an inflammatory reaction in the brain white matter. We report a case of ALD associated with adrenal insufficiency and two autoimmune diseases: vitiligo and ulcerative colitis.

Original languageEnglish (US)
Pages (from-to)169-172
Number of pages4
JournalEuropean Neurology
Volume42
Issue number3
DOIs
StatePublished - Oct 1 1999

Keywords

  • Adrenal insufficiency
  • Adrenoleukodystrophy
  • Demyelination
  • Ulcerative colitis
  • Very long-chain fatty acids
  • Vitiligo

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  • Cite this

    Sawaya, R. A., Mourad, F. H., Najjar, S., Mikati, M., & Raymond, G. V. (1999). Adrenoleukodystrophy associated with vitiligo and ulcerative colitis. European Neurology, 42(3), 169-172. https://doi.org/10.1159/000008093