Increasing numbers of U.S. adolescents are using alternative and complementary therapies, seemingly mirroring the trend among adults. Patterns of use among adolescents may be different from those of adults, however, due to the unique biological, psychological, and social factors affecting this population. Although there is a growing body of literature on utilization and efficacy of alternative and complementary therapies, few studies have included or focused on adolescents. Such research is needed. Social learning theory provides an appropriate theoretical framework to address the complex web of factors underlying health-care-seeking behavior of adolescents, allowing for consideration of the critical factor of individual expectations in their health care choices. Research on adolescents’ utilization of alternative and complementary therapies is important for providers and policy makers concerned with the present and future health of youth.