Adherence to Positive Airway Pressure Therapy in Obesity Hypoventilation Syndrome

Jeremy Wearn, Bimaje Akpa, Babak Mokhlesi

Research output: Contribution to journalReview articlepeer-review

3 Scopus citations


Because of the prevalence of extreme obesity in the United States, there has been an increase in prevalence of obesity hypoventilation syndrome (OHS). There is limited information on the characteristics and pattern of positive airway pressure (PAP) adherence in patients with OHS compared with eucapnic patients with obstructive sleep apnea (OSA). This article discusses in detail the impact of PAP therapy on outcomes in patients with OHS, compares adherence between continuous PAP and noninvasive ventilation in OHS, and compares PAP adherence in patients with OHS to patients with moderate to severe OSA enrolled in clinical trials designed to improve CPAP adherence.

Original languageEnglish (US)
Pages (from-to)43-59
Number of pages17
JournalSleep Medicine Clinics
Issue number1
StatePublished - Mar 1 2021

Bibliographical note

Publisher Copyright:
© 2020 Elsevier Inc.


  • CPAP
  • Compliance
  • Hypercapnia
  • Hypercarbia
  • Noninvasive ventilation
  • Pickwickian
  • Pressure support
  • Sleep apnea

PubMed: MeSH publication types

  • Journal Article
  • Review


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