Adenocarcinoma of the lung presenting as thrombotic thrombocytopenic purpura

Ahmed Dirweesh, Waqas Siddiqui, Muhammad Khan, Praneet Iyer, Marc Seelagy

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


Acquired thrombotic thrombocytopenic purpura (TTP) usually presents as severe microangiopathic hemolytic anemia (MAHA) and thrombocytopenia in a previously healthy individual. It occurs in approximately three in one million adults and 1 in 10 million children annually. The incidence is increased in females and blacks. Diagnosing TTP and initiating therapy with plasma exchange is a must to avoid preventable complications. Acquired thromotic microangiopathy has been linked to collagen vascular diseases, use of certain medications, organ transplants, infections, pregnancy and cancer. We report a rare case of a 56-year-old African American male diagnosed with TTP who found to have an asymptomatic adenocarcinoma of the lung. Prompt cancer management resulted in completed remission of the thrombotic microangiopathy.

Original languageEnglish (US)
Pages (from-to)82-83
Number of pages2
JournalRespiratory Medicine Case Reports
StatePublished - 2017


  • Adenocarcinoma
  • Lung cancer
  • Thrombotic microangiopathy
  • Thrombotic thrombocytopenic purpura

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