Acyclovir susceptibilities of herpes simplex virus strains isolated from solid organ transplant recipients after acyclovir or ganciclovir prophylaxis

G. Boivin; A. Erice; D. D. Crane; D. L. Dunn; H. H. Balfour

doi:10.1128/AAC.37.2.357

Acyclovir susceptibilities of herpes simplex virus strains isolated from solid organ transplant recipients after acyclovir or ganciclovir prophylaxis

G. Boivin, A. Erice, D. D. Crane, D. L. Dunn, H. H. Balfour

Laboratory Medicine and Pathology

Research output: Contribution to journal › Comment/debate › peer-review

25 Scopus citations

Abstract

We determined the acyclovir (ACV) susceptibilities of herpes simplex virus (HSV) isolates (n = 18) recovered from solid organ transplant patients after antiviral prophylaxis with ACV or ganciclovir. All isolates tested were susceptible to ACV (50% inhibitory concentration, <1 μM). A clinical review of patients with HSV disease showed that all improved with specific anti-HSV therapy, and no recurrences were reported.

Original language	English (US)
Pages (from-to)	357-359
Number of pages	3
Journal	Antimicrobial agents and chemotherapy
Volume	37
Issue number	2
DOIs	https://doi.org/10.1128/AAC.37.2.357
State	Published - 1993

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abstract = "We determined the acyclovir (ACV) susceptibilities of herpes simplex virus (HSV) isolates (n = 18) recovered from solid organ transplant patients after antiviral prophylaxis with ACV or ganciclovir. All isolates tested were susceptible to ACV (50% inhibitory concentration, <1 μM). A clinical review of patients with HSV disease showed that all improved with specific anti-HSV therapy, and no recurrences were reported.",

author = "G. Boivin and A. Erice and Crane, {D. D.} and Dunn, {D. L.} and Balfour, {H. H.}",

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AU - Boivin, G.

AU - Erice, A.

AU - Crane, D. D.

AU - Dunn, D. L.

AU - Balfour, H. H.

PY - 1993

Y1 - 1993

N2 - We determined the acyclovir (ACV) susceptibilities of herpes simplex virus (HSV) isolates (n = 18) recovered from solid organ transplant patients after antiviral prophylaxis with ACV or ganciclovir. All isolates tested were susceptible to ACV (50% inhibitory concentration, <1 μM). A clinical review of patients with HSV disease showed that all improved with specific anti-HSV therapy, and no recurrences were reported.

AB - We determined the acyclovir (ACV) susceptibilities of herpes simplex virus (HSV) isolates (n = 18) recovered from solid organ transplant patients after antiviral prophylaxis with ACV or ganciclovir. All isolates tested were susceptible to ACV (50% inhibitory concentration, <1 μM). A clinical review of patients with HSV disease showed that all improved with specific anti-HSV therapy, and no recurrences were reported.

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Acyclovir susceptibilities of herpes simplex virus strains isolated from solid organ transplant recipients after acyclovir or ganciclovir prophylaxis

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