Acyclovir in chickenpox

Richard D. Clover, Raymond F. Ford, Mark Perkins, Ann M. Arvin, Henry H. Balfour, Richard J. Whitley, Lisa M. Dunkle, Harley A. Rotbart, Henry M. Feder, Sandor Feldman, Anne A. Gershon, Moise L. Levy, Gregory F. Hayden, Paul V. Mcguirt, Janna Harris, Philip A. Brunell

Research output: Contribution to journalLetterpeer-review

8 Scopus citations


To the Editor: In recent years there has been a steady increase in the study of antiviral agents for the treatment of common viral infections. Dunkle et al. (Nov. 28 issue)1 reported on a study involving the use of acyclovir in the treatment of the primary varicella–zoster infection, chickenpox. In their well-designed study, they clearly showed that the normal children treated with acyclovir had a reduction in the duration and severity of disease. They further concluded that “since acyclovir treatment interferes with neither the pre-eruption pathophysiology of primary varicella–zoster virus infection nor the subsequent immune response, treatment of chickenpox is.

Original languageEnglish (US)
Pages (from-to)1224-1226
Number of pages3
JournalNew England Journal of Medicine
Issue number18
StatePublished - Apr 30 1992

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