Acyclovir in chickenpox

Richard D. Clover; Raymond F. Ford; Mark Perkins; Ann M. Arvin; Henry H. Balfour; Richard J. Whitley; Lisa M. Dunkle; Harley A. Rotbart; Henry M. Feder; Sandor Feldman; Anne A. Gershon; Moise L. Levy; Gregory F. Hayden; Paul V. Mcguirt; Janna Harris; Philip A. Brunell

doi:10.1056/NEJM199204303261814

Acyclovir in chickenpox

Richard D. Clover, Raymond F. Ford, Mark Perkins, Ann M. Arvin, Henry H. Balfour, Richard J. Whitley, Lisa M. Dunkle, Harley A. Rotbart, Henry M. Feder, Sandor Feldman, Anne A. Gershon, Moise L. Levy, Gregory F. Hayden, Paul V. Mcguirt, Janna Harris, Philip A. Brunell

Laboratory Medicine and Pathology

Research output: Contribution to journal › Letter › peer-review

9 Scopus citations

Abstract

To the Editor: In recent years there has been a steady increase in the study of antiviral agents for the treatment of common viral infections. Dunkle et al. (Nov. 28 issue)¹ reported on a study involving the use of acyclovir in the treatment of the primary varicella–zoster infection, chickenpox. In their well-designed study, they clearly showed that the normal children treated with acyclovir had a reduction in the duration and severity of disease. They further concluded that “since acyclovir treatment interferes with neither the pre-eruption pathophysiology of primary varicella–zoster virus infection nor the subsequent immune response, treatment of chickenpox is.

Original language	English (US)
Pages (from-to)	1224-1226
Number of pages	3
Journal	New England Journal of Medicine
Volume	326
Issue number	18
DOIs	https://doi.org/10.1056/NEJM199204303261814
State	Published - Apr 30 1992

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@article{4fc599a09f1d46d2b4b2f2b823d2452b,

title = "Acyclovir in chickenpox",

abstract = "To the Editor: In recent years there has been a steady increase in the study of antiviral agents for the treatment of common viral infections. Dunkle et al. (Nov. 28 issue)1 reported on a study involving the use of acyclovir in the treatment of the primary varicella–zoster infection, chickenpox. In their well-designed study, they clearly showed that the normal children treated with acyclovir had a reduction in the duration and severity of disease. They further concluded that “since acyclovir treatment interferes with neither the pre-eruption pathophysiology of primary varicella–zoster virus infection nor the subsequent immune response, treatment of chickenpox is.",

author = "Clover, {Richard D.} and Ford, {Raymond F.} and Mark Perkins and Arvin, {Ann M.} and Balfour, {Henry H.} and Whitley, {Richard J.} and Dunkle, {Lisa M.} and Rotbart, {Harley A.} and Feder, {Henry M.} and Sandor Feldman and Gershon, {Anne A.} and Levy, {Moise L.} and Hayden, {Gregory F.} and Mcguirt, {Paul V.} and Janna Harris and Brunell, {Philip A.}",

year = "1992",

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doi = "10.1056/NEJM199204303261814",

language = "English (US)",

volume = "326",

pages = "1224--1226",

journal = "New England Journal of Medicine",

issn = "0028-4793",

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TY - JOUR

T1 - Acyclovir in chickenpox

AU - Clover, Richard D.

AU - Ford, Raymond F.

AU - Perkins, Mark

AU - Arvin, Ann M.

AU - Balfour, Henry H.

AU - Whitley, Richard J.

AU - Dunkle, Lisa M.

AU - Rotbart, Harley A.

AU - Feder, Henry M.

AU - Feldman, Sandor

AU - Gershon, Anne A.

AU - Levy, Moise L.

AU - Hayden, Gregory F.

AU - Mcguirt, Paul V.

AU - Harris, Janna

AU - Brunell, Philip A.

PY - 1992/4/30

Y1 - 1992/4/30

N2 - To the Editor: In recent years there has been a steady increase in the study of antiviral agents for the treatment of common viral infections. Dunkle et al. (Nov. 28 issue)1 reported on a study involving the use of acyclovir in the treatment of the primary varicella–zoster infection, chickenpox. In their well-designed study, they clearly showed that the normal children treated with acyclovir had a reduction in the duration and severity of disease. They further concluded that “since acyclovir treatment interferes with neither the pre-eruption pathophysiology of primary varicella–zoster virus infection nor the subsequent immune response, treatment of chickenpox is.

AB - To the Editor: In recent years there has been a steady increase in the study of antiviral agents for the treatment of common viral infections. Dunkle et al. (Nov. 28 issue)1 reported on a study involving the use of acyclovir in the treatment of the primary varicella–zoster infection, chickenpox. In their well-designed study, they clearly showed that the normal children treated with acyclovir had a reduction in the duration and severity of disease. They further concluded that “since acyclovir treatment interferes with neither the pre-eruption pathophysiology of primary varicella–zoster virus infection nor the subsequent immune response, treatment of chickenpox is.

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U2 - 10.1056/NEJM199204303261814

DO - 10.1056/NEJM199204303261814

M3 - Letter

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AN - SCOPUS:0026589381

SN - 0028-4793

VL - 326

SP - 1224

EP - 1226

JO - New England Journal of Medicine

JF - New England Journal of Medicine

IS - 18

ER -

Acyclovir in chickenpox

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