Acute polyosteal osteomyelitis in a patient with congenital ichthyosis and acute lymphoblastic leukemia

Jakub Tolar, Gary Kravitz, Kevin Walker, Christopher L Moertel

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3 Scopus citations


Osteomyelitis can develop after bacteremia in children and is a rare complication of chemotherapy for acute lymphoblastic leukemia. A child with congenital ichthyosis, acute lymphoblastic leukemia and multifocal hematogenous osteomyelitis is described herein. A breached skin barrier secondary to ichthyosis during induction chemotherapy, coupled with impaired immunity, likely provided the opportunity for bacterial seeding, leading to an extensive multifocal osteomyelitis.

Original languageEnglish (US)
Pages (from-to)813-814
Number of pages2
JournalPediatric Infectious Disease Journal
Issue number8
StatePublished - Jan 1 2001



  • Child
  • Ichthyosiform
  • Intraosseous tobramycin beads
  • Nonbullous congenital ichthyosiform erythroderma
  • Orthopedic
  • Staphylococcus aureus

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