Acute hypertensive response management in patients with acute stroke topical collection on stroke

Syeda L. Alqadri, Varun Sreenivasan, Adnan I. Qureshi

Research output: Contribution to journalArticlepeer-review

26 Scopus citations

Abstract

Acute elevation in blood pressure (acute hypertensive response) is commonly observed in the early period of both ischemic and hemorrhagic stroke. The management of acute hypertensive response depends upon the underlying intracranial pathology. Management of acute hypertensive response has been the focus of many trials and studies such as the SCAST trial, CHHIPS trial, COSSACS trial, INTERACT, and ATACH trial, which are discussed here. However, there were many limitations to these trials including time of presentation, different pathophysiology of ischemic strokes versus hemorrhagic strokes, and patient related factors. Ongoing clinical trials which take these limitations into account include ENCHANTED trial, ATACH II trial, INTERACT 2 trial, and ENOS trial. The results of these trials are expected to modify current guidelines of acute stroke, both ischemic and hemorrhagic, and potentially improve clinical outcomes and quality of life.

Original languageEnglish (US)
Article number426
JournalCurrent Cardiology Reports
Volume15
Issue number12
DOIs
StatePublished - Dec 2013

Bibliographical note

Copyright:
Copyright 2014 Elsevier B.V., All rights reserved.

Keywords

  • Acute ischemic stroke
  • Blood pressure
  • Hematoma
  • Hypertensive response
  • Intracerebral hemorrhage
  • Management
  • Penumbra

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