Acute Human Cytomegalovirus Infection with Bleeding in Iran

Behzad Pourhossein, Farhad Yaghmaei, Saber Esmaeili, Omid Banafshi, Shahla Afrasiabian, Mohammad Reza Shirzadi, Mark Schleiss, Ehsan Mostafavi

Research output: Contribution to journalArticlepeer-review


In December 2011, a 42-year-old male farmer was admitted to a hospital in Sanandaj (Western Iran) with fever and anemia in order to check whether he suffered from some infectious diseases. During the first 3 days after admission, the patient gradually developed progressive oliguria, fever, abdominal pain in the right upper quadrant, leukocytosis with toxic granulation, petechiae and ecchymosis, oral bleeding, and vomiting. The sonographic findings revealed splenomegaly and an increase in the thickness of the gall bladder wall. In order to manage the patient and taking into consideration the most probable differential diagnoses, diagnostic tests were performed on two blood samples collected from him, and real-time polymerase chain reaction for human cytomegalovirus was positive.

Original languageEnglish (US)
Pages (from-to)383-386
Number of pages4
JournalOsong Public Health and Research Perspectives
Issue number6
StatePublished - Dec 1 2014

Bibliographical note

Funding Information:
We would like to express our gratitude to our partners in the Departments of Virology (Dr K. Azadmanesh) and Parasitology (Dr S.R. Naddaf), and the Arboviruses and Viral Haemorrhagic Fever Laboratory (Dr S. Chinikar), who carried out the relevant tests for the patient. We would also like to thank the staff of Tohid Hospital of Sanandaj City and the Health Deputy of Kurdistan University of Medical Sciences, who offered medical services to the patients and conducted necessary follow-ups. Further thanks go to the experts of the Centre for Disease Control (CDC) of the Iranian Ministry of Health and Medical education, for their patient follow-up. These tests were funded by a project approved by the Pasteur Institute of Iran and the Center for Disease Control (grant no. 582 ).

Publisher Copyright:
© 2014.


  • Bleeding
  • Human cytomegalovirus
  • Iran
  • Real-time polymerase chain reaction


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