Acute exacerbation of interstitial lung disease after procedures

Research output: Contribution to journalArticlepeer-review

34 Scopus citations


Interstitial lung disease (ILD) is a category of diffuse parenchymal lung diseases characterized by inflammation and/or fibrosis. The best characterized ILD is idiopathic pulmonary fibrosis (IPF). Acute exacerbation of IPF is a dreaded occurrence with grim prognosis and suboptimal treatment options. There have been recent reports that acute exacerbation can occur in other ILDs (AE-ILD). Of note, some of these acute exacerbations follow lung procedures. This review summarizes the available information on AE-ILD and discusses the procedures reported to cause AE-ILD. We also discuss proposed mechanisms, risk factors, treatment and prognosis. This review should help to inform decision-making about risks versus benefits of procedures that are commonly recommended to diagnose ILD.

Original languageEnglish (US)
Pages (from-to)30-37
Number of pages8
JournalRespiratory Medicine
StatePublished - Apr 2019

Bibliographical note

Publisher Copyright:
© 2019 Elsevier Ltd


  • AE-ILD
  • Acute exacerbation
  • Acute exacerbation of interstitial lung disease
  • Interstitial lung disease
  • Lung biopsy


Dive into the research topics of 'Acute exacerbation of interstitial lung disease after procedures'. Together they form a unique fingerprint.

Cite this