Activity of a nitrofurazone matrix urinary catheter against catheter- associated uropathogens

J. R. Johnson; T. Berggren; A. J. Conway

doi:10.1128/AAC.37.9.2033

Activity of a nitrofurazone matrix urinary catheter against catheter- associated uropathogens

J. R. Johnson, T. Berggren, A. J. Conway

Medicine - Veteran's Administration Medical Center

Research output: Contribution to journal › Comment/debate › peer-review

42 Scopus citations

Abstract

Nitrofurazone-coated urinary catheter segments inhibited 51 (75%) of 70 urinary bacterial isolates from patients with indwelling catheters. Inhibition zones correlated significantly with the nitrofurazone MIC (r² = 0.79, P = 0.0001). All strains except the Pseudomonas spp. were inhibited by ≤64 μg of nitrofurazone per ml. MICs of nitrofurazone and nitrofurantoin correlated significantly (r² = 0.93, P = 0.0001).

Original language	English (US)
Pages (from-to)	2033-2036
Number of pages	4
Journal	Antimicrobial agents and chemotherapy
Volume	37
Issue number	9
DOIs	https://doi.org/10.1128/AAC.37.9.2033
State	Published - 1993

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title = "Activity of a nitrofurazone matrix urinary catheter against catheter- associated uropathogens",

abstract = "Nitrofurazone-coated urinary catheter segments inhibited 51 (75%) of 70 urinary bacterial isolates from patients with indwelling catheters. Inhibition zones correlated significantly with the nitrofurazone MIC (r2 = 0.79, P = 0.0001). All strains except the Pseudomonas spp. were inhibited by ≤64 μg of nitrofurazone per ml. MICs of nitrofurazone and nitrofurantoin correlated significantly (r2 = 0.93, P = 0.0001).",

author = "Johnson, {J. R.} and T. Berggren and Conway, {A. J.}",

year = "1993",

doi = "10.1128/AAC.37.9.2033",

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journal = "Antimicrobial Agents and Chemotherapy",

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publisher = "American Society for Microbiology",

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TY - JOUR

T1 - Activity of a nitrofurazone matrix urinary catheter against catheter- associated uropathogens

AU - Johnson, J. R.

AU - Berggren, T.

AU - Conway, A. J.

PY - 1993

Y1 - 1993

N2 - Nitrofurazone-coated urinary catheter segments inhibited 51 (75%) of 70 urinary bacterial isolates from patients with indwelling catheters. Inhibition zones correlated significantly with the nitrofurazone MIC (r2 = 0.79, P = 0.0001). All strains except the Pseudomonas spp. were inhibited by ≤64 μg of nitrofurazone per ml. MICs of nitrofurazone and nitrofurantoin correlated significantly (r2 = 0.93, P = 0.0001).

AB - Nitrofurazone-coated urinary catheter segments inhibited 51 (75%) of 70 urinary bacterial isolates from patients with indwelling catheters. Inhibition zones correlated significantly with the nitrofurazone MIC (r2 = 0.79, P = 0.0001). All strains except the Pseudomonas spp. were inhibited by ≤64 μg of nitrofurazone per ml. MICs of nitrofurazone and nitrofurantoin correlated significantly (r2 = 0.93, P = 0.0001).

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U2 - 10.1128/AAC.37.9.2033

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M3 - Comment/debate

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AN - SCOPUS:0027244491

SN - 0066-4804

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SP - 2033

EP - 2036

JO - Antimicrobial Agents and Chemotherapy

JF - Antimicrobial Agents and Chemotherapy

IS - 9

ER -

Activity of a nitrofurazone matrix urinary catheter against catheter- associated uropathogens

Abstract

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