Actin-containing matrix associated with the plasma membrane of murine tumour and lymphoid cells

Matthew F. Mescher, Mimi J.L. Jose, Steven P. Balk

Research output: Contribution to journalArticlepeer-review

118 Scopus citations

Abstract

A detergent-insoluble matrix has been isolated from murine tumour cell and lymphocyte plasma membranes. The major components of this matrix include actin and four additional proteins not previously identified as cytoskeletal proteins. Labelling studies indicate that the matrix is located on the inner face of the plasma membrane. A cell-surface glycoprotein, 5′-nucleotidase, remains associated with the isolated matrix.

Original languageEnglish (US)
Pages (from-to)139-144
Number of pages6
JournalNature
Volume289
Issue number5794
DOIs
StatePublished - Dec 1 1981

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