Accurate T1 determination from inversion recovery images: Application to human brain at 4 Tesla

Seong‐Gi ‐G Kim, Xiaoping Hu, Kamil Ugurbil

Research output: Contribution to journalArticlepeer-review

69 Scopus citations

Abstract

It is well known that the signal polarity in inversion‐recovery (IR) images changes with inversion time, complicating the determination of T1 To avoid this problem, a simple subtraction method is implemented. In this method, k‐space data of the longest inversion time are subtracted from the corresponding data of each inversion time. This subtraction yields IR images of same polarity, making it straightforward to derive T1 using a standard fitting routine. Phantom T1 studies with IR Turbo‐FLASH images demonstrate that this technique is robust and accurate. Four Tesla T1 values of the human brain were also determined by this method to demonstrate its in vivo utility.

Original languageEnglish (US)
Pages (from-to)445-449
Number of pages5
JournalMagnetic resonance in medicine
Volume31
Issue number4
DOIs
StatePublished - Apr 1994

Keywords

  • Spin‐lattice relaxation (T)
  • inversion recovery
  • magnetic resonance imaging (MRI)

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