Accuracy of endorectal ultrasonography in preoperative staging of rectal tumors

Julio Garcia-Aguilar, Johan Pollack, Suk Hwan Lee, Enrique Hernandez De Anda, Anders Mellgren, W. Douglas Wong, Charles O. Finne, David A Rothenberger, Robert D Madoff

Research output: Contribution to journalArticlepeer-review

298 Scopus citations

Abstract

PURPOSE: Preoperative staging of rectal tumors is considered essential to tailor treatment for individual patients. The aim of the present study was to evaluate the accuracy of endorectal ultrasonography in preoperative staging of rectal tumors. METHODS: Eleven hundred eighty-four patients with rectal adenocarcinoma or villous adenoma underwent endorectal ultrasonography evaluation at a single institution during a ten-year period. We compared the endorectal ultrasonography staging with the pathology findings based on the surgical specimens in 545 patients who had surgery (307 by transanal excision, 238 by radical proctectomy) without adjuvant preoperative chemoradiation. Comparisons between groups were performed using chi-squared tests and logistic regression analysis. RESULTS: Overall accuracy in assessing the level of rectal wall invasion was 69 percent, with 18 percent of the tumors overstaged and 13 percent understaged. Accuracy depended on the tumor stage and on the ultrasonographer. Overall accuracy in assessing nodal involvement in the 238 patients treated with radical surgery was 64 percent, with 25 percent overstaged and 11 percent understaged. CONCLUSION: The accuracy of endorectal ultrasonography in assessing the depth of tumor invasion, particularly for early cancers, is lower than previously reported. The technique is more precise in distinguishing between benign tumors and invasive cancers and between tumors localized to the rectal wall and tumors with transmural invasion. Differences in image interpretation may in part explain discrepancies in accuracy between studies.

Original languageEnglish (US)
Pages (from-to)10-15
Number of pages6
JournalDiseases of the colon and rectum
Volume45
Issue number1
DOIs
StatePublished - 2002

Bibliographical note

Funding Information:
Supported by a limited grant from the Minnesota Colon and Rectal Foundation. Present address of Drs. Pollack and Mellgren: Department of Surgery, Karolinska University Hospital, Stockholm, Sweden. Present address of Dr. Wong: Division of Colon and Rectal Surgery, Memorial Sloan-Kettering Cancer Center, New York, New York. Address reprint requests to Dr. Garcia-Aguilar: Division of Colon and Rectal Surgery, Mayo Mail Code 450, 420 Delaware Street SE, Minneapolis, MN 55455.

Copyright:
Copyright 2008 Elsevier B.V., All rights reserved.

Keywords

  • Endorectal ultrasonography
  • Rectal neoplasm
  • Rectal tumor
  • Staging

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