Accuracy in the alteration of acetaminophen suppositories

Tae W. Kim, Cheryl L. Rognerud, Ching Nan Ou

Research output: Contribution to journalArticlepeer-review

9 Scopus citations

Abstract

Many pediatric anesthesiologists divide acetaminophen suppositories to achieve an approximate dose. In this three-part study we first surveyed pediatric anesthesiologists regarding their attitudes and frequency of this clinical practice. Second, acetaminophen suppositories were divided for analysis of acetaminophen content. Finally, the accuracy of pediatric anesthesiologists in dividing suppositories was assessed. The survey indicated 50% of anesthesiologists believed acetaminophen was nonuniform and 62% believed the alteration of suppositories was inaccurate. The laboratory investigation revealed uniform distribution of acetaminophen but poor accuracy in achieving the target dose. The findings suggest using only intact suppositories for improved accuracy.

Original languageEnglish (US)
Pages (from-to)1303-1305
Number of pages3
JournalAnesthesia and analgesia
Volume100
Issue number5
DOIs
StatePublished - May 1 2005

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