Abstract
Zalocusky et al. (Nature 531:642–646, 2016) recently showed that activity in D2R+ cells in the nucleus accumbens is associated with loss sensitivity to prior outcomes and reduced subsequent risky choice, and that optogenetic stimulation of these cells decreased risky choices in risk-prone rats. While their findings are important for understanding trait-level risk-taking, future research should aim to examine the neuronal mechanisms of a broader range of facets of gain and loss processing with respect to different potential reference points.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 3-4 |
| Number of pages | 2 |
| Journal | Learning and Behavior |
| Volume | 45 |
| Issue number | 1 |
| DOIs | |
| State | Published - Mar 1 2017 |
| Externally published | Yes |
Bibliographical note
Publisher Copyright:© 2016, Psychonomic Society, Inc.
Keywords
- Dopamine
- Loss sensitivity
- Nucleus accumbens
- Probability discounting
- Risky choice
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