Accelerating amyloid-β fibrillization reduces oligomer levels and functional deficits in Alzheimer disease mouse models

Keyphrases

• Alzheimer's Disease Model 100%
• Functional Deficits 100%
• Nonfibrillar 100%
• Amyloid Fibrillation 100%
• Human Amyloid Precursor Protein 66%
• Assembly State 66%
• Arctic mutation 66%
• Transgenic Mice 33%
• Overexpressing 33%
• Alzheimer's Disease 33%
• Amyloid Plaques 33%
• Mutagenesis 33%
• Therapeutic Intervention 33%
• Neurodegenerative Diseases 33%
• Disease-associated 33%
• Behavioral Deficits 33%
• Relative Abundance 33%
• Neuronal Deficits 33%
• Fibrillization 33%
• Plaque Load 33%
• One-state Reality 33%

Biochemistry, Genetics and Molecular Biology

• Mouse Model 100%
• Amyloid 100%
• Wild Type 66%
• Mouse 66%
• Amyloid Precursor Protein 66%
• Mutagenesis 33%
• Transgenic Mouse 33%

Neuroscience

• Oligomer 100%
• Amyloid 100%
• Alzheimer's Disease 100%
• Amyloid Precursor Protein 66%
• Neurodegenerative Disorder 33%
• Mutagenesis 33%
• In Vitro 33%