Absolute Configuration of the Cancerostatic S(–)‐Isophosphamide

Dorota A. Adamiak; Maira Gdaniec; Krzysztof Pankiewicz; Wojciech J. Stec

doi:10.1002/anie.198005491

Absolute Configuration of the Cancerostatic S(–)‐Isophosphamide

Dorota A. Adamiak, Maira Gdaniec, Krzysztof Pankiewicz, Wojciech J. Stec

Center for Drug Design

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

Structure/activity relations in chiral drugs can only be studied if the absolute configuration is known. The levorotatory form of the cancerostatic isophos‐phamide is shown by X‐ray structure analysis to have the S configuration.

Original language	English (US)
Pages (from-to)	549-550
Number of pages	2
Journal	Angewandte Chemie International Edition in English
Volume	19
Issue number	7
DOIs	https://doi.org/10.1002/anie.198005491
State	Published - Jul 1980

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title = "Absolute Configuration of the Cancerostatic S(–)‐Isophosphamide",

abstract = "Structure/activity relations in chiral drugs can only be studied if the absolute configuration is known. The levorotatory form of the cancerostatic isophos‐phamide is shown by X‐ray structure analysis to have the S configuration.",

author = "Adamiak, {Dorota A.} and Maira Gdaniec and Krzysztof Pankiewicz and Stec, {Wojciech J.}",

year = "1980",

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AU - Gdaniec, Maira

AU - Pankiewicz, Krzysztof

AU - Stec, Wojciech J.

PY - 1980/7

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AB - Structure/activity relations in chiral drugs can only be studied if the absolute configuration is known. The levorotatory form of the cancerostatic isophos‐phamide is shown by X‐ray structure analysis to have the S configuration.

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