Absence of XRCC4 and its paralogs in human cells reveal differences in outcomes for DNA repair and V(D)J recombination

Keyphrases

• X-ray 100%
• DNA Repair 100%
• Recombination 100%
• Human Cells 100%
• XRCC4 80%
• Non-homologous End Joining 40%
• Double-strand Breaks 30%
• Accessory Factor 20%
• Ligase IV 20%
• T Cells 10%
• DNA Recombination 10%
• Gene Targeting 10%
• B Cells 10%
• Genomic Instability 10%
• Human Somatic Cells 10%
• DNA Double-strand Break Repair 10%
• Immunodeficiency 10%
• Higher Eukaryotes 10%
• DNA Double-strand Breaks 10%
• DNA Damage 10%
• Species Differences 10%
• Double-strand Break Repair 10%
• Essential Function 10%
• HCT116 Cells 10%
• Additional Losses 10%
• Microhomology 10%
• LIG4 10%
• Double Duty 10%
• DNA Ligase IV 10%

Immunology and Microbiology

• Human Cell 100%
• X Ray 100%
• Paralogy 100%
• DNA Repair 100%
• DNA End Joining Repair 40%
• Cell Line 20%
• Double Stranded DNA Break 20%
• Immunodeficiency 10%
• B Cell 10%
• Somatic Cell 10%
• Eukaryote 10%
• DNA Recombination 10%
• Genomic Instability 10%
• T Cell 10%
• Gene Targeting 10%