Abscisic acid signaling through cyclic ADP-ribose in plants

Yan Wu, Jennifer Kuzma, Eric Maréchal, Richard M Graeff, Hon Cheung Lee, Randy Foster, Nam Hai Chua

Research output: Contribution to journalArticlepeer-review

331 Scopus citations


Abscisic acid (ABA) is the primary hormone that mediates plant responses to stresses such as cold, drought, and salinity. Single-cell microinjection experiments in tomato were used to identify possible intermediates involved in ABA signal transduction. Cyclic ADP-ribose (cADPR) was identified as a signaling molecule in the ABA response and was shown to exert its effects by way of calcium. Bioassay experiments showed that the amounts of cADPR in Arabidopsis thaliana plants increased in response to ABA treatment and before ABA-induced gene expression.

Original languageEnglish (US)
Pages (from-to)2126-2130
Number of pages5
Issue number5346
StatePublished - Dec 19 1997


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