About-weekly variations in nocturia

Germaine G Cornelissen-Guillaume, David E. Axelrod, Franz Halberg

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


The aim of this study was to assess components of variation in nocturia and to determine any putative geomagnetic influence. A 54-year old man with benign prostatic hyperplasia had recorded for about 4 years the number of times he awoke each night to urinate. The data have been reanalyzed for chronomics, the mapping of time structures (chronomes), involving the computation of least squares spectra of the urinary record and of environmental variables recorded during the same 4-year span. In addition to the previously reported monthly variation, other periodicities have been documented, including two separate components with periods of one week and of a near-week. The precise 7-day period may be a mainly exogenous resonance with external influences such as a weekly social schedule, whereas the near-week may be a partial resonance with natural changes in geomagnetics, reflecting in part changes in other non-photic natural environmental factors.

Original languageEnglish (US)
Pages (from-to)S140-S144
JournalBiomedicine and Pharmacotherapy
Issue numberSUPPL. 1
StatePublished - Oct 2004

Bibliographical note

Funding Information:
Support for this study was provided by the US National Institutes of Health (GM-13981), the University of Minnesota Supercomputing Institute, and the Dr h.c. (mult.) Earl E. Bakken fund.


  • Benign prostatic hyperplasia
  • Chronomics
  • Circaseptan
  • Geomagnetic activity
  • Nocturia


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