ABO phenotype and clinical correlates of COVID-19 severity in hospitalized patients

David J. Hermel; Samantha R. Spierling Bagsic; Carrie L. Costantini; James R. Mason; Zhubin J. Gahvari; Alan Saven

doi:10.2144/fsoa-2021-0045

ABO phenotype and clinical correlates of COVID-19 severity in hospitalized patients

David J. Hermel, Samantha R. Spierling Bagsic, Carrie L. Costantini, James R. Mason, Zhubin J. Gahvari, Alan Saven

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

This study investigates the association between ABO blood phenotype and COVID-19 severity, measured by intensive care unit admission, need for intubation, hospitalization length and death. It further explores clinical predictors of COVID-19 severity within a primarily Hispanic demographic in San Diego County. Materials & methods: We retrospectively reviewed 942 total patients, 473 with available blood type, hospitalized at five Scripps Health hospitals with COVID-19. Results: No significant association was found between ABO phenotype and COVID-19 severity on multivariate analysis, while a diagnosis of anemia and male sex was associated with all severity outcomes on exploratory analysis. Conclusion: Our results provide relevant clinical correlates of COVID-19 severity and help better elucidate the association between ABO phenotype and COVID-19.

Original language	English (US)
Article number	0045
Journal	Future Science OA
Volume	7
Issue number	8
DOIs	https://doi.org/10.2144/fsoa-2021-0045
State	Published - 2021
Externally published	Yes

Bibliographical note

Publisher Copyright:
© 2021 The authors.

Keywords

ABO blood type
COVID-19
Hispanic
San Diego
anemia
male

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.2144/fsoa-2021-0045

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title = "ABO phenotype and clinical correlates of COVID-19 severity in hospitalized patients",

abstract = "This study investigates the association between ABO blood phenotype and COVID-19 severity, measured by intensive care unit admission, need for intubation, hospitalization length and death. It further explores clinical predictors of COVID-19 severity within a primarily Hispanic demographic in San Diego County. Materials & methods: We retrospectively reviewed 942 total patients, 473 with available blood type, hospitalized at five Scripps Health hospitals with COVID-19. Results: No significant association was found between ABO phenotype and COVID-19 severity on multivariate analysis, while a diagnosis of anemia and male sex was associated with all severity outcomes on exploratory analysis. Conclusion: Our results provide relevant clinical correlates of COVID-19 severity and help better elucidate the association between ABO phenotype and COVID-19.",

keywords = "ABO blood type, COVID-19, Hispanic, San Diego, anemia, male",

author = "Hermel, {David J.} and {Spierling Bagsic}, {Samantha R.} and Costantini, {Carrie L.} and Mason, {James R.} and Gahvari, {Zhubin J.} and Alan Saven",

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year = "2021",

doi = "10.2144/fsoa-2021-0045",

language = "English (US)",

volume = "7",

journal = "Future Science OA",

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T1 - ABO phenotype and clinical correlates of COVID-19 severity in hospitalized patients

AU - Hermel, David J.

AU - Spierling Bagsic, Samantha R.

AU - Costantini, Carrie L.

AU - Mason, James R.

AU - Gahvari, Zhubin J.

AU - Saven, Alan

PY - 2021

Y1 - 2021

N2 - This study investigates the association between ABO blood phenotype and COVID-19 severity, measured by intensive care unit admission, need for intubation, hospitalization length and death. It further explores clinical predictors of COVID-19 severity within a primarily Hispanic demographic in San Diego County. Materials & methods: We retrospectively reviewed 942 total patients, 473 with available blood type, hospitalized at five Scripps Health hospitals with COVID-19. Results: No significant association was found between ABO phenotype and COVID-19 severity on multivariate analysis, while a diagnosis of anemia and male sex was associated with all severity outcomes on exploratory analysis. Conclusion: Our results provide relevant clinical correlates of COVID-19 severity and help better elucidate the association between ABO phenotype and COVID-19.

AB - This study investigates the association between ABO blood phenotype and COVID-19 severity, measured by intensive care unit admission, need for intubation, hospitalization length and death. It further explores clinical predictors of COVID-19 severity within a primarily Hispanic demographic in San Diego County. Materials & methods: We retrospectively reviewed 942 total patients, 473 with available blood type, hospitalized at five Scripps Health hospitals with COVID-19. Results: No significant association was found between ABO phenotype and COVID-19 severity on multivariate analysis, while a diagnosis of anemia and male sex was associated with all severity outcomes on exploratory analysis. Conclusion: Our results provide relevant clinical correlates of COVID-19 severity and help better elucidate the association between ABO phenotype and COVID-19.

KW - ABO blood type

KW - COVID-19

KW - Hispanic

KW - San Diego

KW - anemia

KW - male

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ABO phenotype and clinical correlates of COVID-19 severity in hospitalized patients

Abstract

Bibliographical note

Keywords

UN SDGs

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