Abnormalities of in vitro lymphocyte responses during bovine viral diarrhea virus infection

Charles C Muscoplat, D. W. Johnson, J. B. Stevens

Research output: Contribution to journalArticle

30 Citations (Scopus)

Abstract

The usual proliferative response induced by the addition of phytohemagglutinin (PHA) to normal bovine lymphocytes cultured in medium containing bovine fetal serum (BFS) was depressed by the addition of bovine viral diarrhea (BVD) virus. The inhibitory effect appears to be related to the viability of the virus. When heat killed or ultraviolet irradiated virus was used, depression did not occur.

Original languageEnglish (US)
Pages (from-to)753-755
Number of pages3
JournalAmerican Journal of Veterinary Research
Volume34
Issue number6
StatePublished - Dec 1 1973

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Bovine Viral Diarrhea Viruses
Bovine viral diarrhea virus
Virus Diseases
lymphocytes
Lymphocytes
Microbial Viability
viruses
phytohemagglutinin
fetal bovine serum
Phytohemagglutinins
infection
Hot Temperature
viability
Viruses
heat
cattle
Serum
In Vitro Techniques

Cite this

Abnormalities of in vitro lymphocyte responses during bovine viral diarrhea virus infection. / Muscoplat, Charles C; Johnson, D. W.; Stevens, J. B.

In: American Journal of Veterinary Research, Vol. 34, No. 6, 01.12.1973, p. 753-755.

Research output: Contribution to journalArticle

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