Abnormalities of in vitro lymphocyte responses during bovine viral diarrhea virus infection

Charles C Muscoplat, D. W. Johnson, J. B. Stevens

Research output: Contribution to journalArticlepeer-review

32 Scopus citations

Abstract

The usual proliferative response induced by the addition of phytohemagglutinin (PHA) to normal bovine lymphocytes cultured in medium containing bovine fetal serum (BFS) was depressed by the addition of bovine viral diarrhea (BVD) virus. The inhibitory effect appears to be related to the viability of the virus. When heat killed or ultraviolet irradiated virus was used, depression did not occur.

Original languageEnglish (US)
Pages (from-to)753-755
Number of pages3
JournalAmerican journal of veterinary research
Volume34
Issue number6
StatePublished - Dec 1 1973

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