Abnormalities of in vitro lymphocyte responses during bovine viral diarrhea virus infection

Charles C Muscoplat; D. W. Johnson; J. B. Stevens

Abnormalities of in vitro lymphocyte responses during bovine viral diarrhea virus infection

Charles C Muscoplat, D. W. Johnson, J. B. Stevens

Research output: Contribution to journal › Article › peer-review

Abstract

The usual proliferative response induced by the addition of phytohemagglutinin (PHA) to normal bovine lymphocytes cultured in medium containing bovine fetal serum (BFS) was depressed by the addition of bovine viral diarrhea (BVD) virus. The inhibitory effect appears to be related to the viability of the virus. When heat killed or ultraviolet irradiated virus was used, depression did not occur.

Original language	English (US)
Pages (from-to)	753-755
Number of pages	3
Journal	American journal of veterinary research
Volume	34
Issue number	6
State	Published - Dec 1 1973

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@article{59b0193de18a48d3a8491c08375aac20,

title = "Abnormalities of in vitro lymphocyte responses during bovine viral diarrhea virus infection",

abstract = "The usual proliferative response induced by the addition of phytohemagglutinin (PHA) to normal bovine lymphocytes cultured in medium containing bovine fetal serum (BFS) was depressed by the addition of bovine viral diarrhea (BVD) virus. The inhibitory effect appears to be related to the viability of the virus. When heat killed or ultraviolet irradiated virus was used, depression did not occur.",

author = "Muscoplat, {Charles C} and Johnson, {D. W.} and Stevens, {J. B.}",

year = "1973",

month = dec,

day = "1",

language = "English (US)",

volume = "34",

pages = "753--755",

journal = "American journal of veterinary research",

issn = "0002-9645",

publisher = "American Veterinary Medical Association",

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}

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T1 - Abnormalities of in vitro lymphocyte responses during bovine viral diarrhea virus infection

AU - Muscoplat, Charles C

AU - Johnson, D. W.

AU - Stevens, J. B.

PY - 1973/12/1

Y1 - 1973/12/1

N2 - The usual proliferative response induced by the addition of phytohemagglutinin (PHA) to normal bovine lymphocytes cultured in medium containing bovine fetal serum (BFS) was depressed by the addition of bovine viral diarrhea (BVD) virus. The inhibitory effect appears to be related to the viability of the virus. When heat killed or ultraviolet irradiated virus was used, depression did not occur.

AB - The usual proliferative response induced by the addition of phytohemagglutinin (PHA) to normal bovine lymphocytes cultured in medium containing bovine fetal serum (BFS) was depressed by the addition of bovine viral diarrhea (BVD) virus. The inhibitory effect appears to be related to the viability of the virus. When heat killed or ultraviolet irradiated virus was used, depression did not occur.

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M3 - Article

C2 - 4707560

AN - SCOPUS:0015828071

SN - 0002-9645

VL - 34

SP - 753

EP - 755

JO - American journal of veterinary research

JF - American journal of veterinary research

IS - 6

ER -

Abnormalities of in vitro lymphocyte responses during bovine viral diarrhea virus infection

Abstract

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