Abnormal neutrophil chemotaxis and T-lymphocyte function in staphylococcal scalded skin syndrome in an adult patient.

P. K. Peterson, M. Laverdiere, P. G. Quie, L. D. Sabath

Research output: Contribution to journalArticlepeer-review

12 Scopus citations

Abstract

Staphylococcal scalded skin syndrome, a disease rarely reported in adults, developed in a 38-year-old male while on steroid therapy for chronic active hepatitis. Studies of immunologic parameters important in staphylococcal host defense revealed normal opsonic activity and phagocytic function but marked defects in neutrophil chemotaxis and T-lymphocyte function. Compromised host defense appears to play a significant role in the pathogenesis of the syndrome in adults.
Original languageUndefined/Unknown
Pages (from-to)128-131
Number of pages4
JournalInfection
Volume5
Issue number3
StatePublished - 1977

Keywords

  • Adult
  • Chemotaxis, Leukocyte
  • Dermatitis, Exfoliative/co [Complications]
  • Dermatitis, Exfoliative/im [Immunology]
  • Hepatitis B/co [Complications]
  • Humans
  • Lectins/pd [Pharmacology]
  • Male
  • Neutrophils
  • Opsonin Proteins
  • Phagocytosis
  • Staphylococcal Infections/im [Immunology]
  • Staphylococcus aureus/im [Immunology]
  • Stimulation, Chemical
  • T-Lymphocytes/de [Drug Effects]

Cite this