A useful modification of the Evans magnesium halide catalyzed anti-aldol reaction: Application to enolizable aldehydes

Aaron E. May, Nathan T. Connell, Heidi A. Dahlmann, Thomas R. Hoye

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

A practical protocol for use of the magnesium halide catalyzed anti-aldol reaction of an Evans N-acyloxazolidinone with enolizable aldehydes is reported. The yields of anti-aldol adducts for saturated or unsaturated and branched or unbranched aliphatic aldehydes are preparatively useful.

Original languageEnglish (US)
Pages (from-to)1984-1986
Number of pages3
JournalSynlett
Issue number13
DOIs
StatePublished - 2010

Keywords

  • Aldehydes
  • Aldol Reaction
  • Catalysis
  • Halides

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