A useful modification of the Evans magnesium halide catalyzed anti-aldol reaction: Application to enolizable aldehydes

Aaron E. May; Nathan T. Connell; Heidi A. Dahlmann; Thomas R. Hoye

doi:10.1055/s-0030-1258480

A useful modification of the Evans magnesium halide catalyzed anti-aldol reaction: Application to enolizable aldehydes

Aaron E. May, Nathan T. Connell, Heidi A. Dahlmann, Thomas R. Hoye

Chemistry (Twin Cities)

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

A practical protocol for use of the magnesium halide catalyzed anti-aldol reaction of an Evans N-acyloxazolidinone with enolizable aldehydes is reported. The yields of anti-aldol adducts for saturated or unsaturated and branched or unbranched aliphatic aldehydes are preparatively useful.

Original language	English (US)
Pages (from-to)	1984-1986
Number of pages	3
Journal	Synlett
Issue number	13
DOIs	https://doi.org/10.1055/s-0030-1258480
State	Published - 2010

Keywords

Aldehydes
Aldol Reaction
Catalysis
Halides

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abstract = "A practical protocol for use of the magnesium halide catalyzed anti-aldol reaction of an Evans N-acyloxazolidinone with enolizable aldehydes is reported. The yields of anti-aldol adducts for saturated or unsaturated and branched or unbranched aliphatic aldehydes are preparatively useful.",

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author = "May, {Aaron E.} and Connell, {Nathan T.} and Dahlmann, {Heidi A.} and Hoye, {Thomas R.}",

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AU - Connell, Nathan T.

AU - Dahlmann, Heidi A.

AU - Hoye, Thomas R.

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AB - A practical protocol for use of the magnesium halide catalyzed anti-aldol reaction of an Evans N-acyloxazolidinone with enolizable aldehydes is reported. The yields of anti-aldol adducts for saturated or unsaturated and branched or unbranched aliphatic aldehydes are preparatively useful.

KW - Aldehydes

KW - Aldol Reaction

KW - Catalysis

KW - Halides

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