A mouse monoclonal antibody was shown to inhibit platelet aggregation in vitro. The antibody reacts with the surface of platelets as well as other nucleated cells. This reagent appears to offer promise in the study of platelet surface events which initiate function.
Bibliographical noteFunding Information:
This work has been supported by the Arthritis Foundation of Minnesota and National Institutes of Health Grant AM 26683-02. Dr. Messner serves as the Minnesota Arthritis Foundation Professor.