TY - JOUR
T1 - A subcutaneous manifestation of tuberous sclerosis complex in the posterior scalp
AU - Pinker, Bradley M.
AU - Daniel, Renie
N1 - Publisher Copyright:
© 2019 The Authors
PY - 2019/12
Y1 - 2019/12
N2 - Tuberous sclerosis complex (TSC) is an autosomal dominant syndrome due to a mutation in the TSC2 or TSC1 gene. The disease is known to have variable expressivity involving the neurological, cardiovascular, renal, pulmonary, and integumentary systems (Kennedy et al., 2017). We present a case report, and associated literature review, of a toddler with a posterior scalp lesion which was identified as a soft tissue fibroma upon histopathology. Unlike angiofibromas, soft tissue fibromas in the head and neck are not common in patients with TSC. This soft tissue tumor may be considered as one of the major criteria in the diagnosis of TSC.
AB - Tuberous sclerosis complex (TSC) is an autosomal dominant syndrome due to a mutation in the TSC2 or TSC1 gene. The disease is known to have variable expressivity involving the neurological, cardiovascular, renal, pulmonary, and integumentary systems (Kennedy et al., 2017). We present a case report, and associated literature review, of a toddler with a posterior scalp lesion which was identified as a soft tissue fibroma upon histopathology. Unlike angiofibromas, soft tissue fibromas in the head and neck are not common in patients with TSC. This soft tissue tumor may be considered as one of the major criteria in the diagnosis of TSC.
KW - Posterior scalp
KW - Soft tissue fibroma
KW - Tuberous sclerosis complex
UR - http://www.scopus.com/inward/record.url?scp=85072517081&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85072517081&partnerID=8YFLogxK
U2 - 10.1016/j.omsc.2019.100127
DO - 10.1016/j.omsc.2019.100127
M3 - Article
AN - SCOPUS:85072517081
SN - 2214-5419
VL - 5
JO - Oral and Maxillofacial Surgery Cases
JF - Oral and Maxillofacial Surgery Cases
IS - 4
M1 - 100127
ER -
