A study of the urinary porphyrins and porphyrin precursors in patients with malignant disease receiving diethylstilbestrol

A. Theologides, B. J. Kennedy, C. J. Watson

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

Administration of diethylstilbestrol, diethylstilbestrol diphosphate, testosterone propionate and 17 alpha-hydroxyprogesterone-n-caproate did not alter the urinary excretion values for coproporphyrin, uroporphyrin, porphobilinogen and delta aminolevulinic acid in nonporphyric subjects. In 1 patient with latent porphyria a slight increase of δ-ALA was observed after diethylstilbestrol but PBG and porphyrin excretion were unaffected. This individual had received stilbestrol previously over a 2 year period.

Original languageEnglish (US)
Pages (from-to)391-395
Number of pages5
JournalMetabolism
Volume13
Issue number5
DOIs
StatePublished - May 1964

Bibliographical note

Funding Information:
From the Department of Medicine, University of Minnesota Hospital, Minneapolis, nesota . Aided in part bg a grant from the U.S.P.H.S. and by the John am! Mary Porphyria Research Fund of the Dept. of Medicine, Unimrsity 4 Minnesota. Received fot pub&cation Jan. 9, 1964.

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