A study of the urinary porphyrins and porphyrin precursors in patients with malignant disease receiving diethylstilbestrol

A. Theologides; B. J. Kennedy; C. J. Watson

doi:10.1016/0026-0495(64)90112-X

A study of the urinary porphyrins and porphyrin precursors in patients with malignant disease receiving diethylstilbestrol

A. Theologides, B. J. Kennedy, C. J. Watson

Medicine - Hematology, Oncology, Transplant

Research output: Contribution to journal › Article › peer-review

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Abstract

Administration of diethylstilbestrol, diethylstilbestrol diphosphate, testosterone propionate and 17 alpha-hydroxyprogesterone-n-caproate did not alter the urinary excretion values for coproporphyrin, uroporphyrin, porphobilinogen and delta aminolevulinic acid in nonporphyric subjects. In 1 patient with latent porphyria a slight increase of δ-ALA was observed after diethylstilbestrol but PBG and porphyrin excretion were unaffected. This individual had received stilbestrol previously over a 2 year period.

Original language	English (US)
Pages (from-to)	391-395
Number of pages	5
Journal	Metabolism
Volume	13
Issue number	5
DOIs	https://doi.org/10.1016/0026-0495(64)90112-X
State	Published - May 1964

Bibliographical note

Funding Information:
From the Department of Medicine, University of Minnesota Hospital, Minneapolis, nesota . Aided in part bg a grant from the U.S.P.H.S. and by the John am! Mary Porphyria Research Fund of the Dept. of Medicine, Unimrsity 4 Minnesota. Received fot pub&cation Jan. 9, 1964.

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title = "A study of the urinary porphyrins and porphyrin precursors in patients with malignant disease receiving diethylstilbestrol",

abstract = "Administration of diethylstilbestrol, diethylstilbestrol diphosphate, testosterone propionate and 17 alpha-hydroxyprogesterone-n-caproate did not alter the urinary excretion values for coproporphyrin, uroporphyrin, porphobilinogen and delta aminolevulinic acid in nonporphyric subjects. In 1 patient with latent porphyria a slight increase of δ-ALA was observed after diethylstilbestrol but PBG and porphyrin excretion were unaffected. This individual had received stilbestrol previously over a 2 year period.",

author = "A. Theologides and Kennedy, {B. J.} and Watson, {C. J.}",

note = "Funding Information: From the Department of Medicine, University of Minnesota Hospital, Minneapolis, nesota . Aided in part bg a grant from the U.S.P.H.S. and by the John am! Mary Porphyria Research Fund of the Dept. of Medicine, Unimrsity 4 Minnesota. Received fot pub&cation Jan. 9, 1964.",

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doi = "10.1016/0026-0495(64)90112-X",

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TY - JOUR

T1 - A study of the urinary porphyrins and porphyrin precursors in patients with malignant disease receiving diethylstilbestrol

AU - Theologides, A.

AU - Kennedy, B. J.

AU - Watson, C. J.

N1 - Funding Information: From the Department of Medicine, University of Minnesota Hospital, Minneapolis, nesota . Aided in part bg a grant from the U.S.P.H.S. and by the John am! Mary Porphyria Research Fund of the Dept. of Medicine, Unimrsity 4 Minnesota. Received fot pub&cation Jan. 9, 1964.

PY - 1964/5

Y1 - 1964/5

N2 - Administration of diethylstilbestrol, diethylstilbestrol diphosphate, testosterone propionate and 17 alpha-hydroxyprogesterone-n-caproate did not alter the urinary excretion values for coproporphyrin, uroporphyrin, porphobilinogen and delta aminolevulinic acid in nonporphyric subjects. In 1 patient with latent porphyria a slight increase of δ-ALA was observed after diethylstilbestrol but PBG and porphyrin excretion were unaffected. This individual had received stilbestrol previously over a 2 year period.

AB - Administration of diethylstilbestrol, diethylstilbestrol diphosphate, testosterone propionate and 17 alpha-hydroxyprogesterone-n-caproate did not alter the urinary excretion values for coproporphyrin, uroporphyrin, porphobilinogen and delta aminolevulinic acid in nonporphyric subjects. In 1 patient with latent porphyria a slight increase of δ-ALA was observed after diethylstilbestrol but PBG and porphyrin excretion were unaffected. This individual had received stilbestrol previously over a 2 year period.

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SN - 0026-0495

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JO - Metabolism

JF - Metabolism

IS - 5

ER -

A study of the urinary porphyrins and porphyrin precursors in patients with malignant disease receiving diethylstilbestrol

Abstract

Bibliographical note

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