A study of chemical carcinogenesis 4. Synthesis of the carbon‐14 labelled carcinogens 5‐methylchrysene, 2‐methyl‐aniline and 3‐methyl‐2‐naphthylamine

Louis Weiss, Myrna Loy, Stephen S. Hecht, Dietrich Hoffmann

Research output: Contribution to journalArticlepeer-review

11 Scopus citations

Abstract

Procedures were developed for synthesis of the carcinogenic compounds 5‐methylchrysene‐5‐14C, 2‐methylaniline‐methyl‐14C and 3‐methyl‐2‐naphthyl‐amine‐methyl‐14C. In each case, label was introduced with 14CO2 and yields were acceptable for preparation of these compounds for metabolic studies.

Original languageEnglish (US)
Pages (from-to)119-131
Number of pages13
JournalJournal of Labelled Compounds and Radiopharmaceuticals
Volume14
Issue number1
DOIs
StatePublished - 1978

Keywords

  • 2‐Methylaniline
  • 3‐Methyl‐2‐naphthylamine
  • 5‐Methylchrysene
  • Carbon‐14
  • o‐Toluidine

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