A specialized multi-transmit head coil for high resolution fMRI of the human visual cortex at 7T

Shubharthi Sengupta, Alard Roebroeck, Valentin G. Kemper, Benedikt A. Poser, Jan Zimmermann, Rainer Goebel, Gregor Adriany

Research output: Contribution to journalArticle

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Abstract

Purpose To design, construct and validate radiofrequency (RF) transmit and receive phased array coils for high-resolution visual cortex imaging at 7 Tesla. Methods A 4 channel transmit and 16 channel receive array was constructed on a conformal polycarbonate former. Transmit field efficiency and homogeneity were simulated and validated, along with the Specific Absorption Rate, using B1+ mapping techniques and electromagnetic simulations. Receiver signal-to-noise ratio (SNR), temporal SNR (tSNR) across EPI time series, g-factors for accelerated imaging and noise correlations were evaluated and compared with a commercial 32 channel whole head coil. The performance of the coil was further evaluated with human subjects through functional MRI (fMRI) studies at standard and submillimeter resolutions of upto 0.8mm isotropic. Results The transmit and receive sections were characterized using bench tests and showed good interelement decoupling, preamplifier decoupling and sample loading. SNR for the 16 channel coil was∼1.5 times that of the commercial coil in the human occipital lobe, and showed better g-factor values for accelerated imaging. fMRI tests conducted showed better response to Blood Oxygen Level Dependent (BOLD) activation, at resolutions of 1.2mm and 0.8mm isotropic. Conclusion The 4 channel phased array transmit coil provides homogeneous excitation across the visual cortex, which, in combination with the dual row 16 channel receive array, makes for a valuable research tool for high resolution anatomical and functional imaging of the visual cortex at 7T.

Original languageEnglish (US)
Article numbere0165418
JournalPloS one
Volume11
Issue number12
DOIs
StatePublished - Dec 1 2016

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Signal-To-Noise Ratio
Visual Cortex
polycarbonate
Head
Magnetic Resonance Imaging
image analysis
Imaging techniques
Signal to noise ratio
Occipital Lobe
Electromagnetic Phenomena
Noise
Oxygen
Time series
time series analysis
Blood
Chemical activation
testing
oxygen
Research
visual cortex

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A specialized multi-transmit head coil for high resolution fMRI of the human visual cortex at 7T. / Sengupta, Shubharthi; Roebroeck, Alard; Kemper, Valentin G.; Poser, Benedikt A.; Zimmermann, Jan; Goebel, Rainer; Adriany, Gregor.

In: PloS one, Vol. 11, No. 12, e0165418, 01.12.2016.

Research output: Contribution to journalArticle

Sengupta, Shubharthi ; Roebroeck, Alard ; Kemper, Valentin G. ; Poser, Benedikt A. ; Zimmermann, Jan ; Goebel, Rainer ; Adriany, Gregor. / A specialized multi-transmit head coil for high resolution fMRI of the human visual cortex at 7T. In: PloS one. 2016 ; Vol. 11, No. 12.
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