A simple, yet highly accurate, QSAR model captures the complement inhibitory activity of compstatin

Keyphrases

• Amino Acid Residues 25%
• Aromatics 25%
• Basic Amino Acids 25%
• Complement Activation 25%
• Compstatin 100%
• Cyclic Peptoids 25%
• Disulfide Bond 25%
• Geometric Properties 25%
• High Transparency 25%
• Highly Accurate 100%
• Hydrophobic Patch 25%
• Hydrophobicity 25%
• Inhibitory Activity 100%
• Nitrogen Atom 25%
• Patch Size 25%
• Peptide Library 25%
• Phage 25%
• Physicochemical Properties 25%
• QSAR Model 100%
• Quantitative Structure-activity Relationship 25%
• Solvent Accessible Surface Area 25%

Biochemistry, Genetics and Molecular Biology

• Accessible Surface Area 50%
• Amino Acids 50%
• Bacteriophage 50%
• C3b 50%
• Complement Activation 50%
• Cyclic Peptide 50%
• Disulfide Bond 50%
• Hydrophobicity 50%
• Peptide Library 50%
• Quantitative Structure Activity Relation 50%
• Quantitative Structure-Activity Relationship 100%

Pharmacology, Toxicology and Pharmaceutical Science

• Amino Acid 50%
• Bacteriophage 50%
• Complement Component C3b 50%
• Cyclopeptide 50%
• Disulfide Bond 50%
• Hydrophobicity 50%
• Quantitative Structure Activity Relation 50%
• Quantitative Structure-Activity Relationship 100%