A role for glutathione peroxidase in protecting pancreatic β cells against oxidative stress in a model of glucose toxicity

Keyphrases

• Oxidative Stress 100%
• Islet 100%
• Pancreatic Cells 100%
• Glutathione Peroxidase (GSH-Px) 100%
• Glucose Toxicity 100%
• Ribose 57%
• Peroxide 42%
• Pancreatic Islets 28%
• Adverse Effects 28%
• Insulin mRNA 28%
• Insulin Secretion 14%
• Human Islets 14%
• Adverse Consequences 14%
• High Glucose 14%
• Glucose Concentration 14%
• Oxidant Stress 14%
• Induced Oxidative Stress 14%
• Chronic Exposure 14%
• Buthionine Sulfoximine 14%
• Glutathione Synthesis 14%
• HIT-T15 Cells 14%
• Insulin Content 14%
• γ-Glutamylcysteine Synthetase 14%
• Supraphysiological 14%
• Antioxidant Drugs 14%
• Adenoviral Overexpression 14%
• Pancreatic Cell Line 14%

Pharmacology, Toxicology and Pharmaceutical Science

• Glutathione Peroxidase 100%
• Glucotoxicity 100%
• Ribose 80%
• Glucose 80%
• Peroxide 60%
• Peroxidase 60%
• Adverse Event 40%
• Oxidizing Agent 40%
• Insulin 40%
• Messenger RNA 40%
• Long Term Exposure 20%
• Synthetase 20%
• Glutathione 20%
• Buthionine Sulfoximine 20%
• Antioxidant 20%

Biochemistry, Genetics and Molecular Biology

• Oxidative Stress 100%
• Glutathione Peroxidase 100%
• Glucose 100%
• Ribose 66%
• Peroxidase 50%
• Secretion (Process) 33%
• Messenger RNA 33%
• Insulin 33%
• Glutathione Metabolism 16%
• Buthionine Sulfoximine 16%